The Ingredients.

Citicoline has been shown to boost brain cell membrane formation by 26% and brain energy by 13.6%.

Brain Bioactivities:
Citicoline helps energize brain cells, while optimizing the neural electrical impulses that power all thought. Citicoline also helps synthesize phosphatidylcholine (PC), the major phospholipid found in brain cell membranes. In combining brain energy + phospholipid synthesis, citicoline may be uniquely qualified for the intensive task of brain cell regeneration and repair. Citicoline also supports neurotransmitters, including acetylcholine, while supplying brain-protective antioxidant activity.

Potential Nootropic Benefits:
Energizes and enhances mental performance without the crash of stimulants. Citicoline has been shown in human research to promote mood balance, memory, attention, focus and concentration. Long-term, it may help maintain healthy brain function against age-related structural changes and mental decline.

Phospholipids like PS decline in the brain with age, along with many measures of cognitive performance.

Brain Bioactivities:
PS is a phospholipid compound that comprises 15% of the brain's fats. It is concentrated in brain cell membranes, where it helps maintain fluidity, optimizes receptors and promotes neurotransmitters like acetylcholine and dopamine. It supports brain cell energy production by enhancing glucose metabolism. It may increase nerve growth factor (NGF) to support brain cell creation, maintenance and repair. PS also helps immune cells dispose of damaged, toxic brain cells — sparing neighboring brain cells from collateral damage.

Potential Nootropic Benefits:
PS may sharpen memory, slow cognitive decline and promote a positive-minded outlook. It has shown promise for helping elderly subjects with brain degeneration — apparently slowing the progression of memory loss while helping with mood, anxiety, socialization and mental clarity. As a result PS is the only nootropic with an FDA-qualified claim for reducing cognitive decline risk.

Mind Lab Pro®'s Bacopa monnieri has been shown to enhance delayed recall memory, immediate recall memory and learning in clinical research.

Brain Bioactivities:
Bacopa's active bacosides are antioxidants that enhance other brain antioxidants, including superoxide dismutase (SOD) and glutathione peroxidase (GPx). This synergistic antioxidant activity helps protect brain cells from the age-accelerating effects of free radicals. Bacosides also promote acetylcholine, GABA and serotonin — all brain chemicals tied to focused thinking, clear memory and healthy mood.

Potential Nootropic Benefits:
Bacopa has strong ties to memory performance and a long association with new learning and retention. Human research shows Bacopa may slow the rate of forgetting newly acquired knowledge. Researchers have also suggested it may accelerate mental processing, optimize cognition under stress and promote relaxation.

Lion's Mane Mushroom (Yamabushitake) has been linked to significant cognitive improvements that declined after supplementation stopped.

Brain Bioactivities:
A unique mushroom that supports brain health, Lion's Mane supplies active nootropics called hericenones and erinacines. Clinical research suggests Lion's Mane stimulates Nerve Growth Factor (NGF) production, which may help with neural regeneration and myelin nerve sheath synthesis. Optimized NGF may support brain plasticity for storage of new learning and memories, as well as promoting robust brain cell replication and healthy brain cell membrane function.

Potential Nootropic Benefits:
A double-blind, placebo-controlled trial linked Lion's Mane Mushroom to significant cognitive improvements in adults aged 50-80 with mild cognitive impairment. Clinical trial researchers have also suggested that Lion's Mane may help to maintain mood balance.

Maritime pine trees adapted to their salty, windswept environment by developing a powerful protective antioxidant complex in their bark.

Brain Bioactivities:
Supplies a potent complex of proanthocyanidin antioxidants that can cross the blood-brain barrier and help to neutralize the damaging effects of toxic free radicals that are concentrated in the brain. Pine bark extract's proanthocyanidins also signal for the release of nitric oxide (NO) — which relaxes blood vessels and increases blood flow to the brain — enhancing delivery of brain-energizing oxygen and glucose. The bark's additional proanthocyanidin bioactivities combine to provide multi-pathway brain regeneration support that has been suggested to help reverse age-related cognitive decline.

Potential Nootropic Benefits:
Pine bark extract's proanthocyanidin compounds are suggested to enhance mental energy, attention, learning and focus in the short-term; as well as maintain memory, mental clarity and brain health in later years.

L-Tyrosine was found to enhance mental performance with greater benefits recorded as tasks progressed from easier (1-BACK) to more difficult (2-BACK).

Brain Bioactivities:
L-Tyrosine is an amino acid compound used to synthesize catecholamine neurotransmitters involved in memory, mood and mental processing – including dopamine, epinephrine, and norepinephrine. Clinical research suggests L-Tyrosine may counter the impact of brain stress; potentially helping to support synthesis of neurotransmitters that are depleted by high-pressure thinking.

Potential Nootropic Benefits:
Human clinical research has suggested L-Tyrosine may help to promote working memory under multitasking conditions and optimize mental performance under high stress, fatigue and sleep deprivation. In addition to its reputation as a nootropic for maintaining mental performance under stress L-Tyrosine has recently drawn academic interest for its nootropic ability to optimize attention and focus.

Suntheanine® has been shown in human clinical research to enhance alpha brainwaves.

Brain Bioactivities:
L-Theanine helps to increase the activity of alpha brainwaves, which are associated with a state of wakeful relaxation and enhanced creativity. It seems to settle excitable neurotransmitters while promoting calming neurotransmitters like serotonin, dopamine and GABA. L-Theanine has been suggested by researchers to modulate the brain's 'attention circuitry.' It may also protect neurons from damage, potentially helping to maintain clear thinking during the aging process.

Potential Nootropic Benefits:
L-Theanine may instill a state of calm, relaxed tranquillity while simultaneously sharpening attention, alertness and focus. It is used for studying, new learning, creative problem solving, art and other tasks that require quiet contemplation. L-Theanine also helps to reduce the harsh jittery side effects of caffeine.

Rhodiola rosea has been linked to dose-dependent mental energy benefits in human clinical research.

Brain Bioactivities:
Rhodiola rosea is believed to stimulate and sustain cognition-critical neurotransmitters — including norepinephrine, dopamine, and serotonin. It may further optimize these neurotransmitters by helping their transport across the blood-brain barrier. Rhodiola rosea has acetylcholine-protective and antioxidant properties that may help with age-related decline. Most notably, Rhodiola rosea strengthens mental resistance to stress by blunting the release of stress hormones including cortisol. Research suggests Rhodiola rosea's nootropic effects begin within 30 minutes and may last for up to six hours.

Potential Nootropic Benefits:
As a herbal Adaptogen, Rhodiola rosea helps strengthen mental + physical stress resistance while supporting brain energy — promoting clear, calm thinking under taxing conditions. Rhodiola rosea is traditionally used to enhance mental processing, memory, learning, attention span, mood and work capacity. It also gained fame as a legal performance-enhancer among Russian Olympic biathletes and powerlifters.

Mind Lab Pro®'s B6 + B9 + B12 reduces homocysteine — thereby promoting brain chemical synthesis and blood flow to the brain.

Brain Bioactivities:
All B-vitamins contribute to brain health but most research focuses on B6, B9 and B12 — due to their key role in homocysteine metabolism. High homocysteine levels and suboptimal B6, B9 and B12 intake are interconnected and modifiable risk factors for brain degeneration, cerebrovascular concerns, mood imbalance and cognitive decline. Supplemental B6 + B9 + B12 has been shown to help balance homocysteine levels in a healthy range associated with sharp overall mental performance.

Potential Nootropic Benefits:
Mind Lab Pro®'s B6 + B9 + B12 targets homocysteine as a synergistic trio, helping with mental performance concerns related to cognitive decline, brain aging, and poor blood flow to the brain. Vitamins B6 + B9 + B12 have also been shown to promote mood balance, mental energy, information storage and long-range brain health.